The only thing that would rival the sweetness of seeing both the Bush and Clinton dynasties go down in flames would be seeing the whole pundit class disappear from sight. That would be a glorious occasion.
Outside of something completely insane or awesome happening, like Paul or a Moderate winning the GOP nom, Hillary will slog through, win her party's nomination and destroy the Republican candidate. Absolutely destroy.
Bernie is going to put up quite a fight, but he is running an education/purification campaign on a national stage--he doesn't really want to become President.
Anything the Right puts up that is ordinary and/or to the Right of Hillary on every issue will be crushed by the overwhelming force of the Diverse Center-Left majority population of the USA. The RNC has been saying it for 3 years now, they can't win on a national stage unless they do SOMETHING different, and Marco Rubio and Ben Carson, whilst polling well right now due to being relatively unknown, are utterly unelectable when the issues come to the fore.
Being a Social Conservative will lose.
Being a Military Hawk will lose.
At least if nothing pulls them back to the center.
A Kasich, Bush or Rand is the GOP's only hope and it's looking pretty rough going for those three as it is.
And still I will give $75 to Rand tomorrow, because I believe in the Liberty Movement! Go team!