Let us not forget the great St. Irenaeus who also came way before Origen:
St. Irenaeus, ca A.D. 140-202
He took from among creation that which is bread, and gave thanks, saying This is My body." The cup likewise, which is from among the creation to which we belong, He confessed to be His blood. (Against Heresies 4:17:5)
But what consistency is there in those who hold that the bread over which thanks have been given is the body of their Lord, and the cup His blood, if they do not acknowledge that He is the Son of the Creator... How can they say that the flesh which has been nourished by the body of the Lord and by His blood gives way to corruption and does not partake of life? ...For as the bread from the earth, receiving the invocation of God, is no longer common bread but the Eucharist, consisting of two elements, earthly and heavenly... (Against Heresies 4:18:4-5)
If the body be not saved, then, in fact, neither did the Lord redeem us with His Blood; and neither is the cup of the Eucharist the partaking of His blood nor is the bread which we break the partaking of His body... He has declared the cup, a part of creation, to be His own blood, from which He causes our blood to flow; and the bread, a part of creation, He has established us as His own body, from which He gives increase to our bodies. When, therefore, the mixed cup and the baked bread receives the Word of God and becomes the Eucharist, the body of Christ, and from these the substance of our flesh is increased and supported, how can they say that the flesh is not capable of receiving the gift of God, which is eternal life -- flesh which is nourished by the body and blood of the Lord...receiving the Word of God, becomes the Eucharist, which is the body and blood of Christ... (Against Heresies 5:2:2-3)