beware hydrolized protein, y'all

Hell, blood levels of glutamate don't even matter, as it doesn't even pass the blood-brain barrier! http://jn.nutrition.org/cgi/content/full/130/4/1016S This is a major peer reviewed journal.

Take another look at the journal you linked. It does not say "it doesn't even pass the blood-brain barrier"

It is classified similar to L-aspartate which you should know does in fact cross the BBB. Glutamate may need a transporter, may not have a high uptake under "normal" conditions and is manufactured in the brain, but it certainly does cross the blood brain barrier.

The first transport systems to be proposed for the BBB were identified on the basis of results from in vivo uptake studies (Oldendorf 1971Citation , Oldendorf and Szabo 1976Citation , Pardridge 1979Citation ). These transporters include the following:...4) System x-, which mediates sodium-independent, high affinity uptake of amino acids with anionic side chains, including L-glutamate and L-aspartate.

In contrast, L-glutamate and L-aspartate, which can be synthesized readily in brain, show much lower rates of uptake into brain at the BBB (Al-Sarraf et al. 1995Citation and 1997bCitation , Benrabh and Lefauconnier 1996Citation ). For these "dietary nonessential" amino acids, brain supply is governed more by intracerebral synthesis and breakdown.

Alhough L-glutamine shows measurable affinity for System L, Ennis et al. (1998)Citation recently reported that glutamine is actually taken up into brain by a separate sodium-dependent mechanism at the BBB, which they identified tentatively as System N. In other tissues, System N mediates the sodium-dependent transport of L-glutamine, L-histidine and L-asparagine.

Just because certain conditions are required for it to happen, does not allow one to say it does not cross the barrier. It may be somewhat independent of plasma levels and needs the right conditions, but those conditions do occur so it does make it's way into the brain. Additionally there are some areas that are not even subject to the Blood brain barrier:

Although the BBB helps protect most of the brain from changes in circulating plasma L-glutamate, there are a few brain areas that do not contain a BBB (Fig. 2Citation ) and do allow rapid L-glutamate uptake from the circulation (Hawkins et al. 1995Citation ). These are known collectively as "the circumventricular organs" and include the median eminence, area postrema, subfornical organ, subcommissural organ, pineal gland, neurohypophysis and organum vasculosum of the lamina terminalis (Gross and Weindel 1987Citation ). Brain uptake rates for small solutes in these areas exceed those of normal brain by 10- to 1000-fold (Gross et al. 1987Citation , Gross 1991Citation , Hawkins et al. 1995Citation , Shaver et al. 1992Citation ). Once within brain extracellular fluid, solutes can move into adjacent brain areas via intercellular diffusion or via flow along the Virchow-Robin spaces. Such movement has been documented for glutamate and aspartate in animals after high dose amino acid administration (Price et al. 1981Citation and 1984Citation ). The net result is that certain areas of the brain are vulnerable to acute fluctuations in plasma glutamate concentration of large magnitude as a result of "flooding" from the circumventricular organs.
 
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MSG makes food taste better, so people eat more. That seems fairly simple. Good observation.

No, it's an after-effect of eating MSG. You haven't digested your food, mostly cause they gave you that oversized high fructose and ice containing soda that hardens the oils in your stomach making it nearly impossible to pass through your digestive system.. you don't require nutrients that are fortified into the food.. but you're body still thinks that it is hungry. It's a function of chemicals and hormones.

Or alternatively, your body DOES require real nutrients which it is not getting from the poor food that is being eaten and your body does crave the nutrients even though your stomach is full. I'm pretty sure both of these theories work hand in hand, depending on the situation.
 
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The problem with conspiracy theorists in the medical world is that any lies are easy to see through, and are weeded out in the peer review process. You can make wild claims in non-peer reviewed journals, or on random nutjob internet blogs, but nobody should believe anything published there unless the results have been reproduced by others. When you have a lot of eyes on a subject, the likelihood of fraud goes to zero. That is what real science is about. The vast majority of MD's are great at what they do, but science isn't part of their job description. Indeed, they suck at science, moreso even than a joe-off-the-street, because they think they are smarter than everyone else, and many have God complexes. Leave science to the PhDs, but don't take someone at their word just because they have one. Peer review is the only way to prove anything.

Or the opposite of what you say is true, and most studies require funding and said funding is not provided to scientists for peer reviewed studies that are not expected to provide the results that said funding source is looking for. So no good science on these subjects ever comes out because the studies are done intermittently by independent scientists without major funding from the food and drug special interest lobby.
 
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Or the opposite of what you say is true, and most studies require funding and said funding is not provided to scientists for peer reviewed studies that are not expected to provide the results that said funding source is looking for. So no good science on these subjects ever comes out because the studies are done intermittently by independent scientists without major funding from the food and drug special interest lobby.

Not everything in the world is funded by corporations. When you lie about one thing in this world, it is easy to tell, as it will have implications beyond your immediate field. If you start lying about something big like metabolic pathways, it becomes clear really quick, as people will want to cite your paper, and most of the people citing your paper will find that you are wrong, as it affects their results. When that happens (very rare--because it is always found out and the person who did it is utterly ruined), it is damn near always found out.

If you have funding from a different industry, or are working with funding from a national organization such as the NIH (who does not review content prior to publication), then you find a situation where your thesis is that of a crazy person. Sadly, this seems to be par for the course for you, Danno. Hundreds of thousands of scientists are not out to get you. They do not report false data en masse, and they do not cover up for each other. In this world, you get ahead by proving other people wrong. The only exception to this rule that I can think of offhand is climatology, where the whole field was basically founded on the assumption of global warming, and the only source of funding is "liberal" institutions ruled by political appointees who aren't scientists. I'm sure there are other fields like this, but brother let me tell you, human physiology ain't one of the. There are about five hundred times too many people in this field to be manipulated in any manner other than with verifiable fact.

You should go to your local university and sit in on a thesis defense in a hard science field (like cell biology, biochemistry, or genetics to be relevant to this conversation). Watch the professors tear them apart if there is ANYTHING that even LOOKS wrong. Also know that most of the people defending their thesis have already been subjected to two or more years of this type of attack. Science is trial by fire, and scientists as a group are fire hardened. If there was a group of people that is likely to admit that they are wrong in the face of real evidence, scientists are it (though that doesn't always happen--the larger the field, the more likely that the truth will make it through).

Would you really have people take the word of some guy over that kind of accumulated and tested wisdom?
 
God damn it... I had a nice long response and got a security token error. Its gone... its all gone...
 
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