Well, what Ron said in that Larry McDonald speech above is pertinent: run in the party you think you can win.
For some people, that may be the LP. But, that'll definitely be a local thing for you and your best chances will be in smaller towns in rural America.
For everyone else, take your pick but Dems and GOP run the show. I sometimes think we need to go back to the 2007-2012 Ron Paul strategy: take over the local GOPs... We have to admit there were some successes there.
If you want the more cynical approach: none of this really matters. The Doomsday clock is ticking away no matter what.
Or a Christian approach: don't trouble yourself with any of this nonsense. Our kingdom is not of this world and we only have one Lord.