1st Trimester Antidepressant Use Tied to Autism Risk

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A new Johns Hopkins study discovers an association between prenatal exposure to antidepressant medications, autism spectrum disorder (ASD), and developmental delays (DD) in boys.
Researchers from the Bloomberg School of Public Health found that early prenatal exposure to selective serotonin reuptake inhibitors (SSRIs) — commonly prescribed for depression, anxiety, and other disorders — increased the risk for ASD three-fold.

Common SSRIs include citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), paroxetine (Paxil, Pexeva), and sertraline (Zoloft).

The study of 1,000 mother-child pairs is published in the online edition of Pediatrics. In the study, investigators analyzed data from large samples of ASD and DD cases, and population-based controls.
Importantly, researchers used a uniform protocol to confirm ASD and DD diagnoses by trained clinicians using validated standardized instruments.

The study included 966 mother-child pairs from the Childhood Autism Risks from Genetics and the Environment (CHARGE) Study, a population-based case-control study based at the University of California at Davis’ MIND Institute.

http://psychcentral.com/news/2014/0...depressant-use-tied-to-autism-risk/68613.html
 
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